2016.01.22–2016.03.06
Contents
Plomin R, DeFries JC, Knopik VS, & Neiderhiser JM (2012) Behavioral Genetics (6e)
01. Overview
02. Mendel's Laws of Heredity
• Mendel's First Law of Heredity
• • Box 2.1: Gregor Mendel's Luck
• • Huntington Disease
• • Phenylketonuria
• • Box 2.2: How Do We Know That 1 in 50 People Are Carriers for PKU?
• Mendel's Second Law of Heredity
03. Beyond Mendel's Laws
• Genes on the X Chromosome
• Other Exceptions to Mendel's Laws
• • New Mutations
• • Changes in Chromosomes
• • Expanded Triplet Repeats
• • Genomic Imprinting
• Complex Traits
• • Schizophrenia
• • General Cognitive Ability
• • Pea Size
• Multiple-Gene Inheritance
• Quantitative Genetics
• • Box 3.1: Liability–Threshold Model of Disorders
04. DNA: The Basis of Heredity
• DNA
• • Box 4.1: The "Central Dogma" of Molecular Genetics
• Chromosomes
05. Animal Models in Behavioral Genetics
• Quantitative Genetic Experiments to Investigate Animal Behavior
• • Selection Studies
• • Inbred Strain Studies
• Animal Studies for Identifying Genes and Gene Functions
• • Creating Mutations
• • Quantitative Trait Loci
• • Synteny Homology
06. Nature, Nurture, and Human Behavior
• Investigating the Genetics of Human Behavior
• • Adoption Designs
• • Box 6.1: The First Adoption Study of Schizophrenia
• • Box 6.2: Issues in Adoption Studies
• • Twin Design
• • Box 6.3: The Twin Method
• • Combination
07. Estimating Genetic and Environmental Influences
• Heritability
• Interpreting Heritability
• • Box 7.1: Estimating Quantitative Genetic Parameters Directly from DNA
• Environmentality
• • Shared Environment
• • Nonshared Environment
• • Estimating Shared and Nonshared Environmental Influences
• • Identifying Specific Nonshared Environment
• • Identifying Specific Nonshared Environment That Predicts Behavioral Outcomes
• Multivariate Analysis
08. The Interplay between Genes and Environment
• Beyond Heritability
• Genotype-Environment Correlation
• • The Nature of Nurture
• • Three Types of Genotype-Environment Correlation
• • Three Methods to Detect Genotype-Environment Correlation
• • Implications
• Genotype-Environment Interaction
• • Animal Models
• • Adoption Studies
• • Twin Studies
• • DNA
09. Identifying Genes
• Mutations
• Detecting Polymorphisms
• • Box 9.1: DNA Markers
• Human Behavior
• • Linkage: Single-Gene Disorders
• • Linkage: Complex Disorders
• • Association: Candidate Genes
• • Box 9.2: Affected Sib-Pair Linkage Design
• • Association: Genomewide
• • Box 9.3: SNP Microarrays
10. Pathways between Genes and Behavior
• Box 10.1: Levels of Analysis
• Gene Expression and the Role of Epigenetics
• The Transcriptome: Gene Expression throughout the Genome
• • Gene Expression Profiles: RNA Microarrays and Sequence-Based Approaches
• • Genetical Genomics
• • Gene Expression as a Biological Basis for Environmental Influence
• The Proteome: Proteins Coded throughout the Transcriptome
• • The Brain
• • Box 10.2: Endophenotypes
• • Learning and Memory
11. Cognitive Disabilities
• General Cognitive Disability: Quantitative Genetics
• General Cognitive Disability: Single-Gene Disorders
• • Phenylketonuria
• • Fragile X Syndrome
• • Rett Syndrome
• • Other Single-Gene Disorders
• General Cognitive Disability: Chromosomal Abnormalities
• • Down Syndrome
• • Sex Chromosome Abnormalities
• Specific Cognitive Disabilities
• • Reading Disability
• • DF Extremes Analysis
• • Communication Disorders
• • Mathematics Disability
• • Comorbidity among Specific Cognitive Disabilities
• Dementia
12. General Cognitive Ability
• Historical Highlights
• • Animal Research
• • Box 12.1: Francis Galton
• • Human Research
• Overview of Genetic Research
• • Genetic Influence
• • Environmental Influence
• • Assortative Mating
• • Nonadditive Genetic Variance
• Developmental Research
• • Does Heritability Change during Development?
• • Do Genetic Factors Contribute to Developmental Change?
• Identifying Genes
13. Specific Cognitive Abilities
• Broad Factors of Specific Cognitive Abilities
• Multivariate Genetic Analysis
• Information-Processing Measures
• Working Memory Model
• Imaging Genetics
• School Achievement
• Identifying Genes
14. Schizophrenia
• Family Studies
• • Box 14.1: The Beginnings of Psychiatric Genetics: Bethlem Royal and Maudsley Hospitals
• Twin Studies
• Adoption Studies
• Schizophrenia or Schizophrenias?
• Identifying Genes
15. Other Adult Psychopathology
• Mood Disorders
• • Family Studies
• • Twin Studies
• • Adoption Studies
• • Identifying Genes
• Anxiety Disorders
• Other Disorders
• Co-Occurrence of Disorders
• • Identifying Genes
16. Developmental Psychopathology
• Autism
• • Family and Twin Studies
• • Identifying Genes
• Attention-Deficit and Disruptive Behavior Disorders
• • Twin Studies
• • Identifying Genes
• Anxiety Disorders
• Other Disorders
• Overview of Twin Studies of Childhood Disorders
17. Personality and Personality Disorders
• Self-Report Questionnaires
• Other Measures of Personality
• Other Findings
• • Situations
• • Development
• • Nature-Nurture Interplay
• Personality and Social Psychology
• • Relationships
• • Self-Esteem
• • Attitudes and Interests
• • Behavioral Economics
• Personality Disorders
• • Schizotypal Personality Disorders
• • Obsessive-Compulsive Personality Disorder
• • Antisocial Personality Disorder and Criminal Behavior
• Identifying Genes
18. Substance Use Disorders
• Alcohol Dependence
• • Twin and Adoption Research on Alcohol-Related Phenotypes
• • Animal Research on Alcohol-Related Phenotypes
• • Molecular Genetic Research on Alcohol-Related Phenotypes
• Nicotine Dependence
• • Twin Research on Smoking-Related Phenotypes
• • Molecular Genetic Research on Smoking-Related Phenotypes
• Other Drugs
• Complexities of Studying the Genetics of Substance Use
19. Health Psychology and Aging
• Health Psychology
• • Body Weight and Obesity
• • Subjective Well-Being and Health
• Psychology and Aging
• Health Psychology and Genetic Counseling
• • Box 19.1: Genetic Counseling
20. Evolution and Behavior
• Charles Darwin
• Inclusive Fitness
• Population Genetics
• Evolutionary Genomics
• Evolutionary Psychology
• • Instincts
• • Empirical Evidence
• • Box 20.1: Mate Preference and the Major Histocompatibility Complex
• • Box 20.2: Mate Selection for Facial Characteristics
21. The Future of Behavioral Genetics
• Quantitative Genetics
• Molecular Genetics
• Implications of Nature and Nurture
Appendix: Statistical Methods in Behavioral Genetics
• Quantitative Genetics
• Molecular Genetics
Web Sites
Glossary
References
Name Index
Subject Index